FEATURED, Genetics, Genomics, Research
STUDY SUGGESTS BENEFIT OF DRUG TARGETING PIK3CA-MUTATED BREAST CANCER
Located on chromosome 3, PIK3CA is mutated in approximately 40% of patients with hormone receptor (HR) positive, Her2 negative breast cancer. Standard therapy f...
GARBAGE IN. HOW TO RECOGNIZE A DODGY ACADEMIC JOURNAL
This is a short but excellent article from The Economist. It’s worth a quick read.
AXILLARY LYMPH NODE MICROMETASTASIS
IS THERE STILL A NEED FOR POSTMASTECTOMY RADIATION OR COMPLETION AXILLARY LYMPH NODE DISSECTION?
PHENOTYPIC CHARACTERISTICS OF PALB2 RELATED BREAST CANCER
BRCA1 and BRCA2 interact with the PALB2 protein to repair damaged DNA. PALB2 is located on chromosome 16. When located on both alleles, mutations in PALB2 cause...
40 YEAR TRENDS IN POSTMENOPAUSAL HORMONE THERAPY AND THE INCIDENCE OF BREAST CANCER - DISPARITIES EXIST BETWEEN BLACK AND WHITE WOMEN
The Women’s Health Initiative (WHI) initiated 2 randomized trials in 1993. The trials included conjugated equine estrogen (CEE) in postmenopausal women with a p...
THE PLOT THICKENS -ASHKENAZI BRCA GENE MUTATION FOUND IN SEPHARDIC JEWISH PEOPLE SUGGESTS THAT ALL JEWISH PEOPLE SHARE A SIMILAR GENOME
Jewish ethnic divisions refer to separate and someone distinctive Jewish communities. Most if not all of these resulted from the original Israeli diaspora. From...
COVID-19 SURVEY
IMPORTANT: Dr. Fauci says please do not prescribe these medicines willy nilly. Please collect useful data on how people are managing Coronavirus.
FEATURED, Chemotherapy, Neoadjuvant Treatment, Research
Checkpoint Inhibitor Plus Chemotherapy Dramatically Improves Complete Response Rates Over Chemotherapy Alone in Neoadjuvant Setting
Evading the immune system is mandatory for a tumor to progress. To mount an attack on invading tumor cells, T-cells use a cell surface protein called PD-1 (PD, ...
