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FEATURED, Genetics, Genomics, Research

STUDY SUGGESTS BENEFIT OF DRUG TARGETING PIK3CA-MUTATED BREAST CANCER

Located on chromosome 3, PIK3CA is mutated in approximately 40% of patients with hormone receptor (HR) positive, Her2 negative breast cancer. Standard therapy f...

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FEATURED, Research

GARBAGE IN. HOW TO RECOGNIZE A DODGY ACADEMIC JOURNAL

This is a short but excellent article from The Economist. It’s worth a quick read.

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FEATURED, Research

AXILLARY LYMPH NODE MICROMETASTASIS

IS THERE STILL A NEED FOR POSTMASTECTOMY RADIATION OR COMPLETION AXILLARY LYMPH NODE DISSECTION?

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FEATURED, Research

PHENOTYPIC CHARACTERISTICS OF PALB2 RELATED BREAST CANCER

BRCA1 and BRCA2 interact with the PALB2 protein to repair damaged DNA. PALB2 is located on chromosome 16. When located on both alleles, mutations in PALB2 cause...

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FEATURED, Research

40 YEAR TRENDS IN POSTMENOPAUSAL HORMONE THERAPY AND THE INCIDENCE OF BREAST CANCER - DISPARITIES EXIST BETWEEN BLACK AND WHITE WOMEN

The Women’s Health Initiative (WHI) initiated 2 randomized trials in 1993. The trials included conjugated equine estrogen (CEE) in postmenopausal women with a p...

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FEATURED, Genetics, Research

THE PLOT THICKENS -ASHKENAZI BRCA GENE MUTATION FOUND IN SEPHARDIC JEWISH PEOPLE SUGGESTS THAT ALL JEWISH PEOPLE SHARE A SIMILAR GENOME

Jewish ethnic divisions refer to separate and someone distinctive Jewish communities. Most if not all of these resulted from the original Israeli diaspora. From...

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FEATURED, Research

COVID-19  SURVEY

IMPORTANT: Dr. Fauci says please do not prescribe these medicines willy nilly. Please collect useful data on how people are managing Coronavirus.

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FEATURED, Chemotherapy, Neoadjuvant Treatment, Research

Checkpoint Inhibitor Plus Chemotherapy Dramatically Improves Complete Response Rates Over Chemotherapy Alone in Neoadjuvant Setting

Evading the immune system is mandatory for a tumor to progress. To mount an attack on invading tumor cells, T-cells use a cell surface protein called PD-1 (PD, ...

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FEATURED, Research

Invasive Lobular Carcinoma: Features Associated with Late Recurrence (>5 yrs)

 

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FEATURED, Research, Breast Cancer, Risk

Please Don't Say it's Food! Nutrients and Breast Cancer Risk

Studies trying to pin breast cancer risk to intake of various food groups have been to say the least, inconsistent. The authors performed a nutrient-wide associ...

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