FEATURED, Genetics, Genomics, Research
STUDY SUGGESTS BENEFIT OF DRUG TARGETING PIK3CA-MUTATED BREAST CANCER
Located on chromosome 3, PIK3CA is mutated in approximately 40% of patients with hormone receptor (HR) positive, Her2 negative breast cancer. Standard therapy f...
THE PLOT THICKENS -ASHKENAZI BRCA GENE MUTATION FOUND IN SEPHARDIC JEWISH PEOPLE SUGGESTS THAT ALL JEWISH PEOPLE SHARE A SIMILAR GENOME
Jewish ethnic divisions refer to separate and someone distinctive Jewish communities. Most if not all of these resulted from the original Israeli diaspora. From...
FEATURED, Genetics, Genomics, News, Genetic Engineering, Germline
Concerns Rise Following CRISPR Revelation from China
International moratorium called for by CRISPR scientists
INFECTIOUS HEREDITARY
Mendel and his peas - is that all there is? DNA is passed from parent to offspring, a process called vertical gene transfer.
FEATURED, Genetics, Genomics, Genetic Testing
Mutation Predicts Survival but only in ER-positive Patients
IMPLICATIONS OF TP53 SOMATIC MUTATIONS ARE MOLECULAR SUBTYPE SPECIFIC The somatic mutation TP53—in addition to being critical in maintaining the stability of th...
FEATURED, Genetics, Genetic Testing
Why does Vitamin E appear to offer cancer protection for some but worsen the risk for others?
This is an interesting analysis, as it has always bothered me that Vitamin E supplements appear to be cancer-protective in some studies and possibly harmful in ...
FEATURED, Genetics, News, BRCA, Genetic Testing
DIRECT TO CONSUMER GENE TESTING MAY BE A GAME CHANGER
What are your plans for patients who arrive with their genetic profiles? On March 16, 2018, the United States Food and Drug Administration (FDA) authorized 23an...
FEATURED, Genetics, News, Research, Genetic Testing
Obsolete Guidelines for Genetic Testing Miss Breast Cancer Patients Who Could Benefit
Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle? Approximately 330,000 patients are diagnosed with breast cance...
FEATURED, Genetics, Opinion, Research
Somatic Cancer Mutations Accrue Over Years But Not All Become Cancer
Still a mystery why certain somatic mutations become cancerous while others don’t: It’s not merely a numbers game When researchers found that ”Somatic mutant ...
