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FEATURED, Genetics, Genomics, Research

STUDY SUGGESTS BENEFIT OF DRUG TARGETING PIK3CA-MUTATED BREAST CANCER

Located on chromosome 3, PIK3CA is mutated in approximately 40% of patients with hormone receptor (HR) positive, Her2 negative breast cancer. Standard therapy f...

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FEATURED, Genetics, Industry

ONE GENETICS COMPANY HAS STARTED VIRTUAL GENETIC TESTING

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FEATURED, Genetics, Research

THE PLOT THICKENS -ASHKENAZI BRCA GENE MUTATION FOUND IN SEPHARDIC JEWISH PEOPLE SUGGESTS THAT ALL JEWISH PEOPLE SHARE A SIMILAR GENOME

Jewish ethnic divisions refer to separate and someone distinctive Jewish communities. Most if not all of these resulted from the original Israeli diaspora. From...

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Concerns Rise Following CRISPR Revelation from China

FEATURED, Genetics, Genomics, News, Genetic Engineering, Germline

Concerns Rise Following CRISPR Revelation from China

International moratorium called for by CRISPR scientists

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Infectious Hereditary

FEATURED, Genetics, Research

INFECTIOUS HEREDITARY

Mendel and his peas - is that all there is? DNA is passed from parent to offspring, a process called vertical gene transfer. 

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MIGHT SYSTEMIC THERAPY IMPAIR THE SUCCESS OF IMMUNOTHERAPY

FEATURED, Genetics, Genomics, Genetic Testing

Mutation Predicts Survival but only in ER-positive Patients

IMPLICATIONS OF TP53 SOMATIC MUTATIONS ARE MOLECULAR SUBTYPE SPECIFIC The somatic mutation TP53—in addition to being critical in maintaining the stability of th...

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Breast cancer risk with vitamin e

FEATURED, Genetics, Genetic Testing

Why does Vitamin E appear to offer cancer protection for some but worsen the risk for others?

This is an interesting analysis, as it has always bothered me that Vitamin E supplements appear to be cancer-protective in some studies and possibly harmful in ...

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FDA authorized 23andMe to perform direct to consumer BRCA testing

FEATURED, Genetics, News, BRCA, Genetic Testing

DIRECT TO CONSUMER GENE TESTING MAY BE A GAME CHANGER

What are your plans for patients who arrive with their genetic profiles? On March 16, 2018, the United States Food and Drug Administration (FDA) authorized 23an...

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P-LP Variants and NCCN Criteria

FEATURED, Genetics, News, Research, Genetic Testing

Obsolete Guidelines for Genetic Testing Miss Breast Cancer Patients Who Could Benefit

Underdiagnosis of Hereditary Breast Cancer: Are Genetic Testing Guidelines a Tool or an Obstacle? Approximately 330,000 patients are diagnosed with breast cance...

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Somatic Cancer Mutations-120381-edited-317357-edited

FEATURED, Genetics, Opinion, Research

Somatic Cancer Mutations Accrue Over Years But Not All Become Cancer

Still a mystery why certain somatic mutations become cancerous while others don’t:  It’s not merely a numbers game When researchers found that  ”Somatic mutant ...

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