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Friday, January 19, 2018


Hormonal Contraception and Breast Cancer Risk

A new study published in the New England Journal of Medicine, relates results of the Danish Sex Hormone Registry Study follows a national cohort of Danish women between 15 and 79 years of age. A total of 1,797,932 women were included in the study population. A relative risk (RR) of breast cancer among all and current users of hormone contraception was of 1.2. That risk increased from 1.09 with less than 1 year of use to 1.38 with more than 10 years. Even after discontinuation, the risk of breast cancer remained high when comparing never users to those using hormonal contraceptives for 5 years or more. The overall absolute increase among recent and current users of hormonal contraceptives was 13 per 100,000 person-years or approximately 1 extra breast cancer for every 7690 women using hormonal contraception for 1 year.

Morch LS. Contemporary Hormonal Contraception and the Risk of Breast Cancer. NEJM 2017; 377:2228-39.


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